The Hotel Residence Wurzburg is situated right in Old Town Wurzburg, Bavaria, close to several of the town's attractions. In particular, the hotel is near the River Main, the Marienberg Fortress, and the Kappele, an 18th century pilgrimage church, as well as the congress center and plenty of restaurants and other interesting attractions. Guests of the Hotel Residence Wurzburg will be within walking distance of many of Wurzberg's attractions. Guests can also drive to the hotel quite easily.

The rooms of the Hotel Residence Wurzburg are modern and comfortable, and they include amenities like satellite televisions and free Internet access.

Guests of the Hotel Residence Wurzburg can enjoy an on-site restaurant, Joe's Cantina y Bar, which offers Mexican dishes and plenty of mixed drink options. The hotel also include other modern amenities and comforts, including views of the Marienberg Fortress and the Kappele. This hotel is a three-star hotel, which boasts modern amenities in a historical area.